FutuRx Portfolio

A2i Therapeutics Ltd. is a joint venture of FutuRx and Atomwise, designed to utilize Atomwise’s AI platform, AtomNet® technology, to target ADAR1, a key protein involved in controlling the innate immune response, neurological disorders, metabolic diseases and potentially a key target for immuno-oncology and neurological homeostasis. Scientific Approach A2i Therapeutics is developing small molecule inhibitors […]
Bsense Bio Therapeutics is developing small molecules for the treatment of neuropathic pain. Bsense is pioneering a novel approach targeting multiple pain-related mechanisms using a single compound, to achieve greater efficacy and safety.
CSO: Dr. Yael Tsalenchuck CatchMe Therapeutics develops a novel class of precision medicines that targets the epitranscriptome machinery. The emerging field of RNA epitranscriptomics refers to a set of RNA modifying proteins and modified-RNA binding proteins that control different aspects of RNA biology and holds great potential for new cancer therapeutics. Scientific Background During the […]
Circuit-Bio is a synthetic biology company developing an innovative unique platform of logical gene circuits for cancer immunotherapy. The Company’s platform focuses on generating gene circuits able to locally and accurately produce a combination of multiple immune-stimulating proteins (immunomodulators) exclusively expressed in targeted tumor cells. Thus, the circuit selectively converts cancer cells into ‘Trojan horses’ utilize […]
Epeius pharma is a cell and gene therapy company developing next generation biological vehicles for delivery of therapeutic proteins into the central nervous system (CNS). Efficient and predictable therapeutics delivery is particularly challenging in neurological diseases due to the blood-brain barrier (BBB), which tightly regulates the transport of molecules to the brain, and blocks the […]
GliXogen Therapeutics is developing a treatment to enhance remyelination in neurodegenerative disorders which are driven by damage to the neuron’s myelin sheath, such as multiple sclerosis (MS).
JAMM Therapeutics is a drug discovery company developing small molecule modulators of the BRISC deubiquitinating (DUB) enzyme complex, an important regulator of type I interferon (IFN) signaling, for the treatment of systemic lupus erythematosus (SLE) and other autoimmune diseases. Scientific background Type I IFNs are a family of cytokines that are characterized by their antiviral, […]
MOYA Bio is developing a novel class of tumor immune conditioning agents. The company’s first-in-class inhibitors of the FAT10 pathway are envisioned to increase the impact of immunotherapy by sensitizing the tumor to immune-mediated cytotoxicity, to benefit additional patient populations.
GENERAL Ramino Bio is developing an oral drug to treat cancer, metabolic diseases, and rare Maple Syrup Urine Disease (MSUD), characterized by chronic elevated branched-chain amino acids (BCAAs; Valine, leucine, and Isoleucine), which lead to toxic metabolites and alter metabolism. Our unique technology reduces the high circulating BCAAs by increasing their breakdown. The company was […]
RNAble is developing novel compounds that alter RNA stability through modulation of RNA epitranscriptomics for the treatment of specific cancers and rare genetic diseases with nonsense mutations. SCIENTIFIC BACKGROUND RNA transcripts undergo modifications that are recognized by specific RNA binding proteins dictating their stability. Prof. Rotem Karni, RNAble inventor, discovered that targeting components of the […]
Selene Therapeutics is pioneering a new therapeutic strategy for treating refractory epilepsy – regulation of the neuronal activity set point by reduction of the neuronal mean firing rate (MFR). Selene aims to develop small molecule for inhibitors of Dihydroorotate dehydrogenase (DHODH), a mitochondrial enzyme located on the inner mitochondrial membrane and participating in several key […]
Skip Therapeutics develops precision, RNA-based, treatments for rare genetic diseases by applying a novel, proprietary, computational engine to directly identify patient cohorts and determine therapeutic designs. SCIENTIFIC BACKGROUND Thousands of rare genetic disorders affect millions of people worldwide, however the small number of patients for each disease, further segregated by patient-specific mutations, has hindered development […]

Incubator Graduates

Discovering and developing innovative microbiome-based therapeutics to prevent and treat cancer, IBD, and topical diseases that stem from dysbiosis.
ImmPACT-Bio is pioneering a novel strategy to surmount a major challenge compromising current Chimeric Antigen Receptor T-cell (CAR-T) therapy.
Pi Therapeutics is a preclinical-stage pharmaceutical company a first-in-class small molecule cancer drug
Protekt Therapeutics is a biopharmaceutical company aiming to develop a drug for enhancing the long-term memory of those suffering from mild cognitive impairment (MCI)